Future Clinical Trials
نویسندگان
چکیده
منابع مشابه
Evaluation of Clinical Trials
In a number of important clinical issues such as evaluation of the efficacy or effectiveness of therapeutic or preventive interventions as well as for comparing the harms of interventions, randomized controlled trials (RCTs) provide the highest levels of evidence, either directly or indirectly. It is obvious that critical appraisal of these studies to assess their validity and precision is of p...
متن کاملFuture of clinical trials for pulmonary hypertension.
In 1995, the first successful randomized controlled trial (RCT) for pulmonary arterial hypertension (PAH) led to the approval of the pulmonary vasodilator epoprostenol.1 Under the assumption that PAH was a disease of inappropriate pulmonary vasoconstriction, testing a drug that had vasodilator properties seemed reasonable. The 6-minute walk test was the primary end point in the trial because it...
متن کاملClinical Trials Past, Present and Future
The modern concept of testing new treatments in randomised control trials began in 1948 when the Medical Research Council in the UK reported the results of a trial of streptomycin for pulmonary tuberculosis which had been organised by Drs DArcy and Daniels. However, even before this trial started in 1946, another randomised trial had begun to assess the effect of immunisation for whooping coug...
متن کاملDesigning future clinical trials in acute pancreatitis.
Accessible online at: www.karger.com/pan Overall disease-related mortality from an episode of acute pancreatitis is approximately 10% [1]. There are no specific therapies for acute pancreatitis apart from prophylactic antibiotics [2] and endoscopic sphincterotomy [3] for severe gallstone-related disease. The failure of the recent multi-centre study of the platelet activating factor antagonist l...
متن کاملClinical trials: past, present, and future.
Carotid stenting has been in evolution for the past 15 years. Initially limited by a lack of dedicated equipment, pivotal trials using both dedicated stent technology and embolic protection filters in patients at high risk for surgical endarterectomy have been largely completed, and results have compared favorably to both direct and historical surgical controls. While this has led to Food and D...
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ژورنال
عنوان ژورنال: Surgical Oncology Clinics of North America
سال: 2017
ISSN: 1055-3207
DOI: 10.1016/j.soc.2017.05.014